Endocrine Abstracts

Background: In men inhibin B is correlated with sperm count, concentration and testicular volume. Anti-müllerian hormone (AMH) is significantly positively correlated with inhibin B and significantly negatively correlated with FSH. Raised FSH is a traditional marker of infertility. Young male cancer patients treated with gonadotoxic agents are at high risk of hypogonadism (HG). The relationship between inhibin B and AMH with serum total testosterone is unclear.<p class...

Background and AimIt is known that the variability of testosterone concentrations is predictive of both truncal and peripheral obesity in healthy men. The aim of this study was to establish the nature of the relationship between testosterone and fat mass in young male cancer survivors compared with healthy controls.Subjects176 male cancer survivors (mean age 37.3 years SD 5.8) who previously received gonadoto...

Background: Men who receive gonadotoxic treatment for cancer may be at risk of hypogonadism. The extent of this risk is unknown. Severe hypogonadism is associated with fatigue, sexual dysfunction, reduced muscle mass and obesity. Diagnosing mild or moderate hypogonadism is difficult and requires evaluation.Aim: The aim of this study was to identify hypogonadism in young male survivors of cancer.Subjects and Methods: The study was a...

Many risk factors predict fractures overall, but other factors may be associated with the incidence of vertebral fractures in particular. We carried out a 10-year prospective study of a population-based group of women, ages 50 to 85 years. At baseline we measured bone mineral density (BMD) and collected fasting blood samples for biochemical measurements including serum calcium, alkaline phosphatase, parathyroid hormone, creatinine, phosphate, albumin and thyroid hormones. Medi...